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Serological Survey for Rubella and Measles Antibodies Among First Graders

Gilbert M. Schiff, MD; Calvin C. Linnemann Jr., MD; Linda Shea, RN; John J. Witte, MD; John H. Ackerman, MD; Leslie Stapleton; William R. Elsea, MD; Mary Agna, MD
JAMA. 1974;227(1):49-52. doi:10.1001/jama.1974.03230140023005.
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A serological survey to determine susceptibility rates to rubella and measles was conducted among first graders in Cincinnati during 1972. Sixty-three percent (858) of the eligible first graders participated. The overall susceptibility rates to rubella and measles were 21% and 7%, respectively. The susceptibility rate to rubella was down from 75% found among first graders in an adjacent school district in 1968. However, the lower socioeconomic group of first graders had a significantly higher susceptibility rate. The middle socioeconomic group had a significantly higher susceptibility rate to measles. The failure rates for rubella and measles vaccines were 13% and 7%, respectively, indicating a need for follow-up serologic studies to determine persistence of vaccine-induced antibodies.

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