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Dermatology—More Than Skin Deep

Zenonas Danilevicius, MD
JAMA. 1977;237(14):1469-1470. doi:10.1001/jama.1977.03270410069030.
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Research in immunobiology, immunopathology, and immunochemistry has left deep impressions on many of the clinical disciplines. Although tissue and organ transplantation is in the field of surgery, it is tied in deeply with immunological phenomena, especially the graft-vs-host reaction. Changing the patient's immunological status exposes the patient to opportunistic, previously unknown infections. The resistance to various diseases or lack of it is now explained by immunological factors and conditions.

The skin, being a large, important, and more exposed organ than others of the body, depends to a high degree on various immunological changes, degrees of immunity, and the body's own immunological defenses. Some authors have even created a new term, "immunodermatology," which actually describes the interrelation between immunological phenomena and dermatological conditions and their treatment or prevention.

Recently, K. Frank Austen and other prominent immunologists and dermatologists prepared a special issue of The Journal of Investigative Dermatology (September 1976). The


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