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Article |

Fetal Risks in Rubella Vaccination

Murray D. Kuhr, MD
JAMA. 1973;226(11):1357. doi:10.1001/jama.1973.03230110045014.
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To the Editor.—  Data of Wyll and Herrmann (225:1472, 1973) regarding fetal risk in inadvertent rubella vaccination might be interpreted differently. The first risk to the fetus is induced abortion; in this group (50%), the mortality rate was 100%. The outlook for the survivors of this risk is excellent; 11% were spontaneous abortions—a rate better than the spontaneous abortion rate in mothers who did not receive inadvertent rubella vaccination. In the cases resulting in live offspring there was not a single documented case of congenital rubella. All 11 viable offsprings had absence of viral isolation; 12 of 12 had normal cord immunoglobulin M levels; 39 of 39 had normal follow-up examinations at 4 to 20 months; and 96 of 96 had normal examinations at birth. The documented morbidity of inadvertent rubella vaccination early in gestation was nil among those not aborted, even in the susceptible group.Among those aborted, attenuated


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