Two separate periods of my life brought me into frequent contact with Sir William Osler, with ample opportunity to feel and see the influence of his powerful mind and personality on myself, my friends, and colleagues in the Oxford medical school. The first period was when I was a preclinical student in 1905 to 1908. Osler was in his late fifties, and full of vigor, having come to Oxford as Regius Professor of Medicine in 1904. We were a very small band of medical students, not more than 20, I think, in the whole University—itself less than 3,000 students. I myself had taken my degree in jurisprudence (law), and had moved over enthusiastically to medicine. At that time the University offered only a preclinical course, of which, however, the physiology course was reputed the best in the country. In this setting, Osler's clinical preeminence made little impact on us, though