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E. D. Kilbourne, MD
JAMA. 1973;225(6):640-641. doi:10.1001/jama.1973.03220330052031.
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Depending on the severity of its expression as disease, infection with influenza virus can be regarded as nuisance or plague. While most victims experience only brief, if incapacitating febrile illness related to viral replication in the upper respiratory tract and trachea, thousands die each year from the secondary bacterial pneumonias that follow such cytopathic effects, or, less commonly, from primary influenza virus pneumonia. Influenza by the late Professor Mulder and his long-time colleague and collaborator J. F. Ph. Hers, is restricted in its focus as an elegantly presented treatise and atlas of the pathology of fatal human influenza. The reader will search in vain for a clinical description or even a definition of the disease. The complicated epidemiology of this baffling illness is only briefly considered, and the remarkable advances in recent years in the understanding of its causative virus are unmentioned. All of this is regrettable, because Mulder, as


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