A collaborative effort of 11 physicians from the Michael Reese Hospital, this book deals with the management of Rh hemolytic disease. It is limited almost exclusively to the classic problem of Rh0 isosensitization, with only a single, oblique reference to A-B-O hemolytic disease. More esoteric problems, such as hr' or hr" sensitization or iso-sensitization to blood factors of other blood-group systems, are not dealt with at all.
The book emphasizes chiefly problems of extreme Rh sensitization in which there has been a history of previous stillbirths due to Rh hemolytic disease and in which still another stillbirth is anticipated. There are detailed descriptions of amniocentesis and intrauterine transfusion. The authors admit to a 30% operative mortality for this relatively blind procedure; of 24 such transfused babies who were born alive, 12 died, making their total mortality 65%. The gestational age of these 24 babies at delivery, whether by spontaneous