To the Editor:—
This letter reports platelet-isoantigen antibody reaction with its attendant production of thrombocytopenia in the third, fourth, fifth, and sixth siblings born to a single set of parents. The first and second siblings were attended by another physician and the condition of these infants at birth is unknown.Technical details, and a thorough review are supplied by Shulman et al,1 and the present experience emphasizes the possibility of recurrence of the phenomenon within a family.
Report of Cases:—
The mother of the infants was seen for the first time as a gravida 3, para 2, with a normal intrauterine gestation of approximately 4 1/2 months' duration. Her previous obstetrical, medical, and surgical history was not remarkable save for the history of "kidney infection." Her previous two pregnancies, labors, and deliveries were normal and had resulted in children whose growth and development were likewise unremarkable.Following an uneventful