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Article |

Biology of Bone

Reginald R. Cooper, MD
JAMA. 1972;222(10):1313-1314. doi:10.1001/jama.1972.03210100061037.
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Although this relatively brief readable monograph portrays bone "as seen by a histologist," the author takes every opportunity to stress functional implications of structure. A liberal sprinkling of up-to-date references in each short chapter directs the efforts of those who would go deeper into any subject covered.

After a condensed survey of bone function and the history of methods applied to the investigation of bone, the author discusses the traditionally defined varieties of bone. A terse review of matrix and mineral structure and chemistry precedes an enlightening synopsis of bone evolution. The sections on bone deposition and calcification (a term chosen deliberately over the more accurate term "mineralization") place modern views of bone metabolism against the appropriate structural background.

Those interested in justice for the often disregarded and probably vitally important osteocyte will praise the author for his separate albeit short chapter calling attention to this cell. A summary of


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