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ARTICLE |

Behavioral and Physiological Characteristics in Hyperuricemia

Richard R. Lanese, PhD; Glen E. Gresham, MD; Martin D. Keller, MD, PhD
JAMA. 1969;207(10):1878-1882. doi:10.1001/jama.1969.03150230092011.
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A total of 210 white male state employees, aged 40 to 59, participated in a screening program for risk factors for coronary heart disease, and 19.5% were hyperuricemic, defined as a serum uric acid level of 7.0 mg/100 cc or above (enzymatic spectrophotometric method). These hyperuricemic subjects were compared with nonhyperuricemic subjects on the behavioral variables of age, education, conflict, internal versus external control, perception of change with respect to early and present life situations, job stability, cigarette smoking, and physical activity. The physiological variables considered were blood pressure, serum creatinine values, serum cholesterol levels, and ponderal index. Hyperuricemia was associated with increased perception of change, decreased job stability, greater cigarette smoking, elevated blood pressure, and lower ponderal index. These associations suggest the possibility that changing living patterns, particularly in persons of upward mobility, may be an important contributing factor in hyperuricemia.

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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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