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Medical News

JAMA. 1972;221(7):641-648. doi:10.1001/jama.1972.03200200003002.
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Screening test for hepatitis combines sensitivity and speed  An easily-automated system for detecting hepatitis-associated antigen (HAA) combines "the rapidity and simplicity of conventional immunoelectroosmophoresis and the sensitivity of radioimmunoassay."The blood screening test developed by Frank H. DeLand, MD, and Robert Tilden, BS, can also simultaneously detect antibody to the hepatitisassociated antigen.In a presentation at the Society of Nuclear Medicine meeting in Boston, Dr. DeLand said that most American blood banks use immunoelectroosmophoresis (IEOP) or counter-electrophoresis (CEP) in processing some 7 million units of blood each year. However, "CEP fails to detect more than half of the sera positive for HAA." Radioimmunoassays (RIA) are much more sensitive, he admitted, but are usually too complicated and time-consuming for mass screening.For example, immunoelectroosmophoresis takes 1 1/2 hours but it is generally thought to be only ten times more sensitive than the least sensitive agar gel diffusion technique. Compared to agar


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