Most physicians see only a small group of leukemias in a lifetime of practice, but are profoundly affected by those they do see. Each patient presents his own difficult and eventually insoluble problems. Negative prognosis is inherent in the diagnosis. The practitioner, therefore, thinks of the leukemias of experimental animals as models which may some day lead to better understanding of the causes of these terrible diseases in man, to better methods of treatment, eventually perhaps even to means of cure and of prevention.
Rich's Experimental Leukemia will therefore probably have little appeal to the average physician, or even to the clinical hematologist. The editor of this compendium of observations on leukemia in experimental animals has gone out of his way to avoid mention of human disease. Upton and Cosgrove, for instance, in their chapter on radiation-induced leukemia, make no mention of the extensive studies among the victims of the