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February 10, 1969, Vol 207, No. 6 >
ARTICLE | February 10, 1969

Palliative Irradiation

Luther W. Brady, MD
JAMA. 1969;207(6):1134-1135. doi:10.1001/jama.1969.03150190056013.
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ABSTRACT

During the last decade, advances in radiotherapy have extended the possibilities of treatment of carcinoma of the bladder. Supervoltage and megavoltage modalities now offer means to deal with more advanced tumors with radiation dosages that could not ordinarily be delivered by orthovoltage techniques. These improved methods of treatment allow better dosage distribution within the volume being irradiated with reduction in the severity of the immediate reactions.

Patients with locally advanced cancers of the bladder limited to the pelvis (stage D1) deserve a careful attempt at definitive or curative radiation therapy. The best candidates are those patients who are in good general condition, whose bladder capacity is greater than 100 ml, or whose bladder function is not seriously impaired and who have no urethral obstruction. Treatment should be carried out with proper attention to local bladder anesthetics and control of urinary frequency and dysuria which might interfere with sleep and systemic

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