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January 27, 1969, Vol 207, No. 4 >
ARTICLE | January 27, 1969

The Low-Tryptophan Diet In Psoriasis

Harry Spiera, MD; Albert M. Lefkovits, MD
JAMA. 1969;207(4):758. doi:10.1001/jama.1969.03150170084027.
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To the Editor:—  A Communication by Drs. Petrozzi and Rosenbloom regarding negative results in the dietary treatment of psoriasis (205:345, 1968) calls for several pertinent comments.The results of tryptophan analysis reported by Drs. Petrozzi and Rosenbloom substantially duplicate and confirm findings published earlier by us in which we stated that repetition of our original analysis, using a nitrogen atmosphere, disclosed the presence of substantial amounts of tryptophan in turkey.1 At that time, we stated that the remissions observed in psoriatic patients "cannot be ascribed to tryptophan deprivation." Cognizance of our corrected findings was subsequently noted by a number of publications.2In reference to the reports of Drs. Petrozzi and Rosenbloom, we would like to offer some further comments. In case 1 of their series, the patient was undergoing reduction of steroid therapy while being started on dietary therapy. Such reduction is known to cause exacerbation of

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