JAMA. 1968;206(8):1784-1785. doi:10.1001/jama.1968.03150080064016.
Text Size: A A A
Published online

Since Gajdusek and Zigas1 first described the disease in 1957, kuru has occasioned much painstaking research and a great deal of interest and speculation. Yet kuru's etiology has remained even more mysterious than the highland regions of New Guinea where the disease is found. Recently, researchers have suggested that cannibalism plays a role in transmission of this obscure disorder.

Kuru attacks children of both sexes and women; practically no adult males are affected. Onset is slow, without noticeable prodromata. Death occurs in nearly all cases, and usually within a year of onset. Pathologically, the disease is an apparently unique form of cerebellar degeneration. The symptoms are those of increasing incoordination, ataxia, dysarthria, varied tremors, and emotional lability.2 There is no sensory disturbance.

This remarkable disease seems to have been infrequent two to three generations ago, although this point will probably never be certain. Kuru is limited to a


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours




Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.