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Systemic Lupus Erythematosus Complicated by Coccidioidomycosis

Carl Z. Berry, MD; Lawrence C. Goldberg, MD; William L. Shepard, MD
JAMA. 1968;206(5):1083-1085. doi:10.1001/jama.1968.03150050071021.
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In 1950 this patient was treated with cortisone acetate for acute systemic lupus erythematosus (SLE). A state of remission was obtained until June 1963 when the patient moved to Tucson, Ariz. At this time, there was a relapse of the SLE. By Sept 30, pulmonary coccidioidomycosis developed, and by February 1964 the patient manifested the disseminated form of this disease. By Dec 15, a total of 2,285 mg of amphotericin B had been administered. Both diseases have remained in remission with residuals of nephrotic syndrome, persistent anemia, and leukopenia.

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