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ARTICLE |

Secondary Syphilis With Unusual Clinical and Laboratory Findings

Laszlo Biro, MD; Ann C. Hill, MD; Emanuel G. Kuflik, MD
JAMA. 1968;206(4):889-891. doi:10.1001/jama.1968.03150040101027.
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Physical examination of a patient yielded cutaneous findings suggestive of lymphoma or sarcoidosis. A roentgenogram of the chest revealed nodular infiltrates at the bases of both lungs, lending support for the diagnosis of sarcoidosis. On biopsy, skin lesions showed noncaseating granulomata. The correct diagnosis of syphilis was first suspected on the basis of a reactive Venereal Disease Research Laboratory test. Clinically, atypical forms of syphilis may be on the rise because of short-term antibiotic treatment given to patients during the incubation period of the disease.

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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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