We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......

Management of Clinical Tetanus

Henry Brown, MD
JAMA. 1968;206(2):375. doi:10.1001/jama.1968.03150020091026.
Text Size: A A A
Published online


To the Editor:—  The reference for terms aluminum phosphate adsorbed toxoid and alum toxoid is given (Levine, et al: New Eng J Med274:186, 1966). As explained, these toxoids precipitated by aluminum phosphate or hydroxide are by custom referred as "alum toxoids." Their action is the same clinically.In tetanus prophylaxis in a nonimmunized patient when human hyperimmune serum is not available, from a practical standpoint one thoroughly cleanses and debrides the wound. There is then no devascularized or devitalized tissue to harbor clostridia. One must administer antibiotics before bacterologic reports are available, recognizing, as in all infections, that some strains may be resistant. Usually within 24 hours one can obtain human sera.It is customary to repeat antiserum in treating clinical tetanus because one cannot be certain more organisms are not present, and particularly with animal sera, one cannot be certain how long such antibodies will remain in


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.