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Pathologic Spectrum of Neoplasms of the Nasal Cavity and Paranasal Sinuses

Morgan Berthrong, MD
JAMA. 1972;219(3):339-341. doi:10.1001/jama.1972.03190290033010.
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There are few neoplasms unique to the nasal cavity of paranasal sinuses. Certain unusual clinicopathologic features, however, result from the nature of the local anatomy and the proximity of these areas to the orbital and oral cavities and to the base of the skull. Biologic behavior is also influenced by the anatomic problems of adequate surgical removal of benign neoplasms which may recur and raise questions of low-grade malignancy. A brief discussion of neoplasms seen in these areas can mention only a few of the interesting and important aspects of their biologic course; details must be sought in review articles.5,6

Inflammatory polyps, usually allergic, are exceedingly common in both areas; while these lesions often show squamous metaplasia of the surface epithelium or profound vascular proliferation, they usually do not mimic neoplasia. Epithelial papillomas, however, are probably true neoplasms. These are most common in the nasal cavity but also occur


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