To the Editor:—
The management of the patient with lymphoma depends upon the clinical stage. Among currently available procedures, lymphangiography has been shown to be the only accurate method of staging lymphomas.1 This procedure, however, has been associated with complications, and mortality has been reported.2We have been interested in finding a chemical test which might be helpful in staging lymphomas. Serum mucoid valves have been reported to be increased in a variety of diseases, including malignancies.3 In some studies, levels of serum mucoids paralleled the extent of the malignancy.4 The present study was undertaken to determine whether measurement of serum mucoids would give an accurate assessment of lymphoma stage.
Materials and Methods:—
The diagnosis in all patents were confirmed by biopsy. Patients were categorized into stages I, II, III, and IV as recommended by the Committee on Staging of the American Cancer Society.5Lymphangiograms