We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Marfan's Syndrome

J. Douglas Lee, MD
JAMA. 1971;218(4):597. doi:10.1001/jama.1971.03190170075032.
Text Size: A A A
Published online


To the Editor.—  In a recent report (217:335,1971) a 26-year-old man with "Marfan's Syndrome with Complete Heart Block and Junctional Rhythm" was described. The diagnosis of Marfan's syndrome was based on arachnodactyly, dolichocephaly, congenital cataracts, high arched palate, absence of subcutaneous tissue, and arm span greater than height by 5 cm.This diagnosis must be questioned.The Marfan syndrome is a heritable disorder of connective tissue with characteristic ocular, skeletal, and vascular abnormalities. The patient described had arachnodactyly and dolichocephaly and the quoted indexes support this. Cataracts in patients with the Marfan's syndrome only occur secondary to the uveitis, retinal detachment, and glaucoma resulting from ectopia lentis. Cataract without ectopia lentis is not a part of this syndrome. A cardiac catheterization study revealed no aortic dilatation or insufficiency nor any valvular lesion to support the diagnosis in this patient of Marfan's syndrome.In the absence of a family history


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.