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Article |

Inflammation, Immunity, and Hypersensitivity

Frank W. Fitch, MD
JAMA. 1971;217(1):84-85. doi:10.1001/jama.1971.03190010066036.
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An impressive array of authors have contributed the 11 chapters of this monograph which deals with the acute inflammatory process and with much of what is currently called immunopathology. Originally intended as part of a large treatise on general pathology, the present volume was prepared when plans for the larger text had to be abandoned. The topics covered in this volume have traditionally been considered together, and this relationship is most appropriate since a number of recent observations make it clear that complement components play major pathogenetic roles in a variety of inflammatory processes and that biologically important interrelationships exist between complement, coagulation, and fibrinolytic systems.

The long first chapter deals with general aspects of the acute inflammatory reaction; vascular phenomena in inflammation and mechanisms by which inflammatory exudates and infiltrates occur are considered in detail, with emphasis on the chemical mediators of the reactions. Rather basic aspects of immunology


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