We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Combination Therapy in Head and Neck Cancer

Bernard S. Aron, MD; Vicharn Lorvidhaya, MD
JAMA. 1975;233(2):177-178. doi:10.1001/jama.1975.03260020063031.
Text Size: A A A
Published online


CANCER in the head and neck area is relatively easy to diagnose and usually remains localized; few patients die from distant metastases. However, it remains an important cause of morbidity and mortality in the United States. The American Cancer Society estimates that there will be 32,400 new cases in 1975 and that 11,450 patients will die from this disease.

Surgery and radiation therapy have proved effective methods of therapy; chemotherapy may be useful in the future. These three modalities have their greatest effectiveness on different portions of the tumor: surgery in removing the central core, radiation in destroying the peripheral margin, and chemotherapy in ablating microscopic metastases.

Small early epithelial cancers (T1, N0 [tumor-node classification according to the American Joint Committee for Cancer Staging and End Results Reporting, 1968]) in the head and neck region are adequately treated by either surgery or radiation therapy, with high local


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.