0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Endoscopic Brush Cytology in Esophageal Cancer

Sidney J. Winawer, MD; Paul Sherlock, MD; Joseph A. Belladonna, MD; Myron Melamed, MD; Edward J. Beattie Jr., MD
JAMA. 1975;232(13):1358. doi:10.1001/jama.1975.03250130042020.
Text Size: A A A
Published online

CYTOLOGIC specimens and biopsy specimens obtained by direct endoscopic visualization now provide improved sampling for accurate pathologic evaluation in patients with cancer of the upper part of the gastrointestinal tract.1-3

Materials and Results  Thirty consecutive patients with esophageal cancer are included in this article. All were examined with a forward-viewing upper gastrointestinal tract panendoscope. Multiple biopsy specimens, usually four, and brushings for cytology are obtained in all patients. A sheathed brush was used for the cytology specimens, and slides were prepared individually in 95% ethyl alcohol without air-drying, and processed with the standard Papanicolaou stain. Biopsy specimens were fixed in 10% buffered formalin.Of the 30 patients, 18 had neoplasms at the cardioesophageal junction associated with varying degrees of obstruction. The remainder had neoplasms distributed in the mid and upper parts of the esophagus. Twenty neoplasms were epidermoid, and ten were adenocarcinoma. One adenocarcinoma was in situ in Barrett

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

* * SCHEDULED MAINTENANCE * *

Our websites may be periodically unavailable between midnight and 04:00 ET Thursday, July 10th, for regularly scheduled maintenance.

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();