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The Treatment of Hyperthyroidism

David H. Solomon, MD
JAMA. 1967;201(5):330-331. doi:10.1001/jama.1967.03130050064027.
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To the Editor:—  The editorial "Treatment of Hyperthyroidism" in the April 10 issue presented a one-sided viewpoint. The following points may be cited: (1) The ten-year incidence of hypothyroidism after 131I treatment, cited in the editorial as 70%, is actually about 30% for centers using 7,000 R.1,2 (2) Doses more than 100 mc of 131I, stated in the editorial to be "often" required, are actually rarely used except in hyperthyroidism associated with multinodular goiter.3 (3) In citing which patients have a higher incidence of 131I-induced hypothyroidism, the author's inclusion of the phrase "... in younger patients" ignores the very credibly presented evidence of Green and Wilson showing the opposite, that patients over 40 have an especially high incidence of late hypothyroidism after 131I treatment.1 There is a difference of opinion here: Beling and Einhorn report increased sensitivity of the young thyroid gland to 131


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