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Successful Skin Graft in Patient with Generalized Scleroderma

Bernard E. Herman, M.D.; Roben Fischt, M.D.; Albert Frankel, M.D.; Paul Herman, M.D.
JAMA. 1962;182(5):578-579. doi:10.1001/jama.1962.03050440070021d.
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INDOLENT ULCERS caused by sclerodermatous changes in the skin usually occur on the fingers, toes, knees, or elbows, and infrequently occur elsewhere. As they may be refractory to the usual conservative measures, the following case is presented to illustrate the successful application of a skin graft to an ulcer on the leg of a patient with generalized scleroderma. Search of the literature failed to reveal cases of ulcération due to scleroderma treated successfully by skin grafting.

Report of a Case

This was the third Mount Sinai Hospital admission of a 20-year-old housewife. Her chief complaint was an ulcer adjacent to the right medial malleolus which did not heal in spite of 4 months of intensive therapy in the outpatient clinic. Approximately years before her admission, the diagnosis of scleroderma was made by biopsy at Mount Sinai Hospital. At that time she noticed hardness and stiffness of the skin of her


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