In the past, the practice of surgical pathology as a unit has revolved about the traditional facets of gross examination, microscopic description, histologic diagnosis, and clinical follow-up. Although these are still extremely vital service functions representing the core of clinical practice, they are not enough. This approach is to be likened to the presentation of general pathology as an extension of morbid anatomy in contrast to a dynamic introduction to clinical disease. Here, now, there are a number of investigative techniques which have immediate application to diagnosis, therapy, or basic investigation. All of these techniques are within the expanding domain of the surgical pathologist, for he is in the unique position of having full access to daily volumes of sterile fresh human tissues or fluids. All of us must increase our facilities to better utilize the material presented to us. However, to create time, we must curtail inconsequential, traditional duties