The Stomach and Anaemia

Paul G. Hattersley, MD
JAMA. 1967;200(5):422. doi:10.1001/jama.1967.03120180110036.
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Monographs on highly specialized subjects often make rather dry reading unless the author writes with style, as well as with interest and authority. With his 27 years experience at Oxford and a personal bibliography which includes scores of pertinent titles, Dr. Witts writes about the stomach and anemia with obvious interest and authority. The result is a highly valuable compendium of facts. Stylish writing is not his forte, however, and the text plods just a bit.

The author seriously questions the validity of the concept of "achlorhydria" as traditionally determined by a single body dose of histamine, and he emphasizes the superiority of the "augmented histamine test." He very thoroughly describes pernicious anemia, its pathogenesis, diagnosis, and natural history. Quite properly, he emphasizes the importance of recognizing pre-anemic cases, and points out that carcinoma of the stomach occurs much more commonly in persons with pernicious anemia than in others of


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