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Keratoconjunctivitis as a Diagnostic Aid in Measles

Alfred L. Florman, M.D.; Howard J. Agatston, M.D.
JAMA. 1962;179(7):568-570. doi:10.1001/jama.1962.03050070077019.
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CONJUNCTIVITIS and photophobia are among the classical signs and symptoms of measles. The photophobia usually disappears when the rash fades, and it is thought to be due to keratitis. Every case of measles studied early in its course by Thygeson was found to have keratitis. What is not generally known is that signs of keratoconjunctivitis may appear in the prodromal stages of measles and persist for as long as 3 months. Because these signs may be found even in modified measles, their presence may serve as a useful and prompt clinical aid to diagnosis in doubtful situations. It is the purpose of this communication to describe and differentiate the keratoconjunctivitis of measles as seen by slit-lamp biomicroscopy and to report our experience with 34 children.

Origin and Plan of Study

Our attention was directed to this condition in the spring of 1961 by 2 children who had complained for several


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