For the researcher desiring a comprehensive reference concerning the laboratory mouse as a model system for observing health and disease processes, this book is an excellent choice. It contains enough literature review to allow a search forward and backward for documentation, and detail is complemented by substantial records of unpublished material.
This extensive revision of the original 1941 edition, of the same title, has been accomplished by staff of the Jackson Laboratory in Maine, where a large repository of information upon the laboratory mouse is maintained. Dominant orientation of the book concerns inbred strains of mice, with new information relevant to biochemical and hemoglobin traits, genetic factors governing transplantation of tissues, neurologic mutants. The least altered material deals with embryology, reproduction, and microscopic anatomy with minimal treatment of gross systemic anatomy.
The book, greatly expanded in scope, content, and illustrative material, is organized sequentially into sections on techniques of husbandry