Long-Term Contraception Near?
A "second generation" of contraceptive drugs, emphasizing long-term antifertility, is appearing on the clinical horizon.Planned Parenthood Physicians, meeting in Atlanta, were told:
Discussing the possibility of implantable contraceptives, investigators from the Population Council, New York City, noted that the efficacy of daily, minute oral doses of progestogen—less than a milligram—has been proved extensively. Several field trials of this contraceptive approach have been conducted, including that in Mexico City by Jorge Martinez-Manatou, MD.Animal studies now indicate that the so-called mini-dose also can be dispensed through an implanted silastic capsule, injected microspheres, or similar techniques. "We need
Implantable, sustained release preparations, which could provide contraception for a year, may be ready for early clinical trial within six months.
Two injectable contraceptives so far have proven safe and acceptable in clinical trials ranging up to three years; but further study is required before general clinical use.