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JAMA. 1962;179(3):210-214. doi:10.1001/jama.1962.03050030024005.
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Carcinoma of Skin in Bovine Exposed to Radioactive Fallout  Col. Carl F. Tessmer, MC, U.S. Army, and Daniel G. Brown, D.V.M., Oak Ridge, Tenn.THE RELATION of carcinoma of the skin to radiation has been established in general terms. It was reported in human cases a relatively short time after the discovery of x-rays, from what, by present-day standards, were repeated large doses to the skin.1,2 The similar effect of radioactive materials was soon noted.3 Experimental verification of the carcinogenic action of x-rays was reported in animals in 1910 with the production of sarcoma in rats4 and of the carcinogenic effect of radioactive substances in 1918.5 Carcinoma following single exposures is an established pattern in the skin under certain conditions, as in single doses of beta radiation.6,7 Exposure to radioactive fallout at the skin surface may represent what is customarily viewed as a single

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