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Bone Marrow Embolism Following Closed Chest Cardiac Massage

Erwin C. Winkel, M.D.; Wilson G. Brown, M.D.
JAMA. 1961;178(3):329-331. doi:10.1001/jama.1961.73040420023019b.
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PULMONARY artery bone marrow embolism is a rarely reported entity. In most cases it has been associated with fractures of bones containing red marrow, and may or may not have been a contributing cause of death. In the following case, bone marrow emboli were found in the pulmonary vascular bed as an unsuspected finding in a patient who died of coronary artery thrombosis with associated myocardial infarct, and who had received terminal closed chest massage at the time.

Report of a Case 

Clinical Aspects.—  A 61-year-old female was awakened from her sleep with severe pain across the posterior aspect of her shoulders. She was seen almost immediately by her physician who found her in obvious pain and in shock. There was no history of trauma. She improved on nitroglycerin and morphine sulfate, and within the hour was admitted to the hospital. Review of systems was noncontributory, except that she did


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