ALTHOUGH the procedure of angiography was suggested as early as 1927 by Moniz, it was not widely used in this country for almost 20 years. During the past 10 or 12 years widespread adoption of this diagnostic measure has occurred, but, surprisingly, few studies of large series of angiograms have been carried out, particularly with the use of the contrast material sodium diatrizoate (Hypaque sodium). For these reasons we have recently reviewed over 500 angiographic procedures, with particular reference to the accuracy of the procedures and the risks involved.
The material consists of 540 carotid angiograms carried out on 456 patients during the past 3 years; that is, from 1956 to 1959, at the Western Pennsylvania Hospital and the Presbyterian Hospital of Pittsburgh. Of these, 537 were percutaneous; 3 were open angiograms. In all, 50% diatrizoate was used, in amounts varying from 16 to 120 cc. at a single session.