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Thesaurosis Caused by Hair Spray

Matthew J. Brunner, M.D.
JAMA. 1961;176(12):1055. doi:10.1001/jama.1961.03040250081032.
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To the Editor:—  In an editorial in The Journal, Nov. 5, 1960, entitled "Dangerous Dusts and Furtive Fumes—`New' and Resurrected," pulmonary thesaurosis, believed due to hair spray, is referred to as a new but definitely established clinical entity. It should be made clear to readers of The Journal that the concept of pulmonary thesaurosis is not proven, and that studies by the FDA and others do not confirm its existence.Bergmann and his co-authors originally described pulmonary thesaurosis in a report covering 2 patients in whom x-rays revealed slowly resolving hilar node enlargement and reticulated pulmonary densities. A third possible case was reported in Great Britain. In one subject, a scalene node biopsy showed epithelioid cells containing periodic acid-Schiff stain-positive granules. Both patients had been users of hair spray. Bergmann also injected 3 guinea pigs subcutaneously with hair-spray solids and reported finding a granulomatous reaction at the injection sites.The


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