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JAMA. 1961;176(5):442-443. doi:10.1001/jama.1961.03040180044015.
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Environmental extremes of heat and cold have long intrigued physiologists and clinicians. The changes in the early phases of exposure to critical meteorologic stress are physiological and reversible. The well-developed clinical entities, in some instances, may be reversible under proper treatment. Heat stroke and frostbite are examples of morbidity following temperature stress that leave irreparable sequelae. The physiological and pathological effects of heat and cold have been a life-time program of study by Professor Yas Kuno, initially a member of the Departments of Physiology of the Manchurian Medical College and Kyoto University, and in later years, a member of the Department of Physiology of Nagoya University School of Medicine. His monumental treatise, The Physiology of Human Perspiration, was published in London in 1934. Note was taken at the time of his 77th birthday by the publication of a tribute entitled Essential Problems in Climatic Physiology.1 The monograph, edited by


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