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March 4, 1961, Vol 175, No. 9 >
Other Articles | March 4, 1961

Radiation Injury in Man: Its Chemical and Biological Basis, Pathogenesis and Therapy

Marshall Brucer, M.D.
JAMA. 1961;175(9):826. doi:10.1001/jama.1961.03040090086032.
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ABSTRACT

There are three concepts of radiation injury. A radical group in Oak Ridge believes that it takes a large amount of radiation to cause clinical (as opposed to political) damage. A moderate group in Los Alamos believes moderate exposure causes injury, and a conservative group represented by the authors (Brookhaven) believes that an exposure of only a few hundred roentgens can cause clinical damage.

There are also three concepts of therapy for radiation injury. One group, mainly European, uses drugs in profusion. A second group is looking for "pie in the sky." They believe in imminent "breakthroughs"—tomorrow. A third group believes that therapy is only symptomatic and palliative. The authors of Radiation Injury in Man belong with these but emphasize that some of the symptomatic therapy is lifesaving when given at the proper time for the proper purpose.

The book is primarily a monograph on the effects of radiation as

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