This book, a prize winner in a contest sponsored by the Medical Journal of the Institute of Pension and Retirement for State Employees, is a study in five parts. Part 1 deals with generalities regarding Asian influenza and the role of the World Health Organization during the 1957 epidemic. Part 2 concerns the history and epidemiology of the epidemic which began in China and spread to the entire world. The disease entered Brazil through the southern border in the autumn of 1957. Part 3 deals with the laboratory investigations. Parts 4 and 5 constitute the original contributions in this work, which are the experimental, virological and serologic studies made at the Institute of Microbiology.
The material for the immunogenic study of the influenza outbreak in Rio de Janeiro, in 1957, consisted of paired serums, one in the acute and one in the convalescent phase. They came from patients at the