Forty-eight embolectomies were performed in 38 patients selected for operation by the authors, depending largely on the status of epicritic sensation in the affected extremities. Little diagnostic or therapeutic help was obtained from sympathetic block procedures. Where epicritic sensation was normal or absent only in the metacarpus or metatarsus, a conservative regimen was followed. The operative procedure always included a complete flushing out of all clotted material from the distal arterial tree. Of 43 extremities saved out of the 53 extremities in jeopardy, half were arteriosclerotic and half rheumatic; of the 10 extremities lost, 7 were arteriosclerotic. The arteriosclerotic group of patients had more extensive disease, were older, and were generally in poorer condition than the rheumatic group.