A. Grunwald, M.D.; Z. Silberman, M.D.
JAMA. 1959;171(16):2210-2213. doi:10.1001/jama.1959.73010340003013a.
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The anterior tibial syndrome was first described by Vogt1 in 1943. Further examples of this peculiar syndrome soon appeared. Horn1A published reports of two cases, Phalen2 four cases, Hughes3 three cases, Pearson3A one case, and Carter and co-workers4 collected nine cases, two of which were fully documented. Blandy and Fuller5 described three cases of necrosis of the leg muscles, naming the condition "March gangrene." In two of the cases only the peroneal muscles were involved. A review of the available literature showed that a total of 40 case reports have been published so far.

This condition usually appears in young males who are not used to exercising their leg muscles. After strenuous exercise, such as a game of football or a long march, in the case of soldiers, there is a sudden onset of severe pain in the anterolateral aspect of the leg,


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