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PULMONARY GRANULOMA DUE TO BRUCELLOSIS

Simon J. Ramah, M.D.; Bernhard Chomet, M.D.; James McLean, M.D.; Catherine Lemke, M.S.
JAMA. 1959;170(14):1665-1667. doi:10.1001/jama.1959.63010140005011b.
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Brucellosis has long been known to involve the lungs in varied forms. Haden and Kyger1 reviewed several hundred case records of brucellosis of the lung and reported the findings of seven cases in detail. The latter included pleural effusion, pneumonia, hilar and bronchovascular infiltration, and also pulmonary granuloma. The diagnosis of pulmonary brucellosis was made on the basis of clinical characteristics, a positive brucellin skin test, and the exclusion of other disease. The causative agent was not recovered from any of the patients reported. Greer2 in 1956 surveyed 59 cases diagnosed as pulmonary brucellosis. In his series the findings were those of perihilar and peribronchial infiltration, patchy pneumonia, pleural effusion, empyema, and single granuloma. The diagnosis of pulmonary brucellosis was based on the history and physical findings, blood cultures, and skin, agglutination, and opsonocytophagic tests.

In 1956 Weed and co-workers3 reported three cases of chronic localized pulmonary

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