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July 4, 1959, Vol 170, No. 10 >
ARTICLE | July 4, 1959

BLOOD DISAPPEARANCE OF RADIOACTIVE ROSE BENGALRAPID SIMPLE TEST OF LIVER FUNCTION

Robert A. Nordyke, M.D.; William H. Blahd, M.D.
JAMA. 1959;170(10):1159-1164. doi:10.1001/jama.1959.03010100021008.
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The rate of disappearance of radioactive rose bengal dye from the blood, determined by a simple counting method at the head, provides a sensitive test of liver function. Because dye levels do not depend on color comparisons, the test can be used despite the presence of jaundice. Multiple tests may be done without harm to the patient and can be carried out serially. One hundred five patients with various liver diseases were compared with normal subjects in this study. Results suggest that the test may supplement or replace the sulfobromophthalein test in the evaluation of borderline liver dysfunction.

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