In recent years the concept of allergy has begun to permeate many fields of medical research and clinical medicine, including infectious diseases, collagen disturbances, and autoimmune manifestations. These trends are reflected in this book. The symposiums presented deal with asthma, emphysema, the properties of allergic antibodies, recent advances in clinical allergology, the biochemical aspects of hypersensitivity (histamine, serotonin, acetylcholine, and slow-reacting substance), and autoimmune and isoimmune reactions (blood, encephalomyelitis, kidney, lupus and other collagen diseases, and homografts), atopic dermatitis, and allergic problems in different parts of the world. The contributors to this volume include Sir Henry Dale, Pasteur Vallery-Radot, Charles Loeffler, Peter Forsham, Elvin Kabat, Merrill Chase, Pierre Grabar, C. Jimenez-Diaz, Harry Alexander, Murray Peshkin, H. O. Schild, Richard Schayer, Bernard Halpern, W. D. M. Paton, Robert Good, W. J. Harrington, Max Samter, J. Dausset, P. Miescher, Guy Voisin, Marion Sulzberger, W. Jadassohn, R. L. Mayer, Bram Rose, William Sherman,