This book is divided into (1) historical survey; (2) reports of chemical, clinical, and physiological studies on lysergic acid diethylamide (LSD-25), mescaline, epinephrine metabolites, chelation, serotonin, indole, and central and peripheral fluids; (3) neuroleptic patients; (4) genetic, biological, and philosophical considerations of schizophrenia; (5) surveys of theoretical and methodological aspects of the problem; and (6) a general appraisal by Gilbert Cant, the medicine editor of Time. It is pointed out that "Any illness, including mental illness, can be discussed in a variety of ways: chemical, biological, pharmacological, sociological, through to psychology, philosophy and religion, not to mention medicine and psychiatry"; that biological and chemical theories concern the present symposium; that current chemical theories chiefly envision endogenous toxic factors resulting either from imbalances of chemical substances normally occurring in the body or from the development of new substances; and that the new chemical approach arose from the observation of the psychotomimetic