Streptomycin and Dihydrostreptomycin

This book provides a clear and reasonably complete exposition of the history, properties, methods of susceptibility-testing and assay, bacterial resistance and synergism with other antimicrobials, pharmacology, untoward reactions, and uses in various types of clinical infections, including application in combination with other antibiotics, of streptomycin and dihydrostreptomycin. A brief final chapter describes the use of streptomycin in the isolation and culture of viruses. Although the authors have not attempted to review all previously reported studies, the book takes into account most of the important published papers on the streptomycins. It is unfortunate that no reference was made to the study reported by Wier and co-workers (Dis. Chest30:628-632 [Dec.] 1956) which revealed that, from the standpoint of hearing impairment only, therapy with the combination of streptomycin-dihydrostreptomycin ( Streptoduocin ) may be more hazardous than with streptomycin alone. The bibliography provided is extensive and is annotated in the text. A subject index