The Amphetamines: Their Actions and Uses

This is an interesting, expertly written summary of the significant biological and chemical aspects of the amphetamines. Special emphasis is given to the three members of this group most widely used in medical practice: amphetamine sulfate, dextroamphetamine sulfate, and methamphetamine hydrochloride. The book is designed chiefly for use by practicing physicians, but it should also aid others associated even indirectly with the medical profession. In a touching dedicatory preface Dr. Leake pays well-deserved tribute to Dr. Gordon Alles who synthesized amphetamine in 1927 and made the original pharmacological studies on it. There are chapters on the history, source, and physical properties of the amphetamines; their absorption, fate, and excretion; their pharmacology and toxicology; their therapeutic applications (this is the subject of the longest chapter); and the sociological impact of their use and abuse. While about 300 references are listed, the book does not purport to be a detailed review. It