This edition of a well-known book brings the material up to date. The general format has remained unaltered, but important additions have been made in the sections on bile pigment metabolism, druginduced jaundice, and hepatic coma. The section on jaundice in infancy has been expanded to include a general discussion of hepatic disease in childhood. Much other new material has been added, including electron microscopy of the liver cell, serum transaminases, circulatory phenomena in liver failure, penicillamine in dermatitis exfoliativa, and epidemiology in primary hepatic cancer. More than 500 new references and 37 new figures have been added. This book continues to be one of the best general treatises on liver disease. The style is clear and concise and the material is presented in such a way as to be useful to the practitioner as well as to the specialist in the field. It is highly recommended.