0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

SOME RECENT ADVANCES IN NUTRITION

Tom D. Spies, M.D.
JAMA. 1958;167(6):675-690. doi:10.1001/jama.1958.02990230001001.
Text Size: A A A
Published online

A large part of human disease is chemical rather than bacterial in origin, and in diseases of chemical origin the trouble may be either excess or deficiency. Twelve case histories are here given to illustrate the fact that deficiency states resulting from poor diets are still important and sometimes puzzling. Mental symptoms disappeared when a man was finally treated with nicotinic acid for a long-standing dermatitis which was pellagra. A man of excessively frugal habits suffered from spells of increasing weakness; he was able to return to work after a series of hemorrhages led to the diagnosis of scurvy, which was remedied promptly by the oral administration of ascorbic acid. In many cases, however, the deficiency is more complex; the effect on the patient is a general biological blight, and a spectacular response follows the administration of complex foodstuffs such as nonfat dry milk solids. In some deficiencies anorexia and glossitis are prominent symptoms; breaking this vicious circle with folic acid in one case led to the appearance of a voracious appetite and the complete restoration of a patient who had been near death from severe macrocytic anemia. The body cells can recover to an amazing degree from these chemical upsets. The deficiency diseases bring crushing burdens and stark tragedies; their prevention is a significant part of actual medical practice.

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();