This book summarizes current information concerning the chemistry, physiological effects, pharmacology, and clinical significance of levarterenol ( l-norepinephrine) bitartrate. In 1946 the author first presented evidence that levarterenol was the major pressor amine involved in the chemical transmission of adrenergic nerve impulses. Over 700 references are included in the bibliography, and numerous excellent illustrations are presented. A minor defect is the wide use of the initials A and NA for epinephrine and l-norepinephrine respectively. The highly technical nature of the book will probably appeal to the research worker rather than to the clinician, but the latter should find several chapters, particularly those devoted to the association of levarterenol and pheochromocytomas and to the therapeutic uses of levarterenol, of great interest.