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Herman Schwartz, M.D.; Andrew de Roetth Jr., M.D.; Emanuel M. Papper, M.D.
JAMA. 1957;165(2):144-146. doi:10.1001/jama.1957.02980200024007.
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In patients with glaucoma some confusion exists regarding the parenteral use of atropine and scopolamine as preanesthetic medication for nonocular surgery. This study suggests that there is no danger in using the belladonna drugs intramuscularly for preoperative medication. A single dose of atropine sulfate (up to 0.6 mg.) and scopolamine hydrobromide (up to 0.6 mg.) may be used. Pilocarpine hydrochloride (1 to 2%) or physostigmine salicylate (0.25% to 1%) should be instilled into the conjunctival sac to produce miosis to counteract the potential mydriatic effect of the belladonna drugs and the anesthetic agents.


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