This new edition of a textbook, first published at the turn of the century, is written by one of the founders of American pharmacology. As one indication of the speed with which pharmacology is moving, it might be pointed out that probably over 50% of the drugs in popular use today were not known when the last edition of this book was published in 1948. The aim of this textbook "is to furnish a guide through the complexities of modern pharmacology—the actions and uses of drugs," in association with a critical summary of the chief features of the many contributions made in this ever expanding field. It is presumably prepared primarily for use by medical students. The book is well indexed and, as is to be expected with a book of this type, it is indexed in terms of drugs rather than of diseases for which the drugs are used.